Pemetrexed injection is a chemotherapy drug manufactured and marketed by Natco India. Its indications are the treatment of pleural mesothelioma and non-small cell lung cancer.
Pemetrexed is also recommended in combination with carboplatin for the first-line treatment of advanced non-small cell lung cancer. However, the relative efficacy or toxicity of pemetrexed-cisplatin versus pemetrexed-carboplatin has not been established beyond what is generally thought about cisplatin or carboplatin doublet drug therapy.